Publications

The National Bridges to Health Segmentation Dataset has been used as the key data source for a number of landmark analyses which have both informed and supported NHSE teams and have led to peer reviewed publications in medical journals. See below for links to these publications:

Years lived with and years lost to multiple long-term condition combinations that include diabetes

Nature Medicine | August 2024

An increase in obesity-driven early onset type 2 diabetes has occurred alongside diversification of the multiple long-term condition (MLTC) combinations associated with diabetes. Understanding the burden with regards to years lived with and years of life lost due to specific disease combinations is therefore essential, but was previously difficult due to the absence of a sufficiently large dataset. The National Bridges to Health Segmentation Dataset was used to quantify the burden of diabetes-associated MLTC among a population of 46 million adults in England.

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The burden of diabetes-associated multiple long-term conditions on years of life spent and lost

Nature Medicine | August 2024

Diabetes mellitus is a central driver of multiple long-term conditions (MLTCs), but population-based studies have not clearly characterized the burden across the life course. We estimated the age of onset, years of life spent and loss associated with diabetes-related MLTCs among 46 million English adults.

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Prediabetes, participation in the English National Health Service Diabetes Prevention Programme, and associations with COVID-19-related mortality: A whole population study

Diabetes Research and Clinical Practice | June 2024

Assessment of the effects of non-diabetic hyperglycaemia (NDH, also known as pre-diabetes), including the impact of the NHS Diabetes Prevention Programme (NHS DPP), on COVID-19-related mortality during the pandemic. Younger people with diagnosed NDH were at higher relative risk of COVID-19 mortality. Attendance at the NHS DPP was associated with significantly lower COVID-19-related mortality.

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Prevalence of multiple long-term conditions in England: a whole population study of over 60 million people

Journal of the Royal Society of Medicine | March 2024

While most health systems internationally have evolved to provide diagnosis and management for single chronic conditions, there is a growing concern about the increase in people with multiple long-term conditions (MLTC), also termed multimorbidity. People with MLTC have poorer health-related quality of life, poorer physical function, greater psychological needs, greater use of healthcare services and higher mortality. Healthcare needs for people with MLTC are often complex, presenting a key challenge for the future of healthcare systems globally.

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Associations of type 1 and type 2 diabetes with COVID-19 – related mortality in England: a whole-population study

The Lancet Diabetes and Endocrinology | October 2020

Although diabetes has been associated with COVID-19-related mortality, the absolute and relative risks for type 1 and type 2 diabetes are unknown. We assessed the independent effects of diabetes status, by type, on in-hospital death in England in patients with COVID-19 during the period from March 1 to May 11, 2020.

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